Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation

The lymphatic vasculature is essential for maintaining interstitial fluid homeostasis, and dysfunctional lymphangiogenesis contributes to various pathological processes, including inflammatory disease and tumor metastasis. Mutations in FOXC2 are dominantly associated with late-onset lymphedema; howe...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Fatima, Anees, Wang, Ying, Uchida, Yutaka, Norden, Pieter, Liu, Ting, Culver, Austin, Dietz, William H., Culver, Ford, Millay, Meredith, Mukouyama, Yoh-suke, Kume, Tsutomu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922698/
https://ncbi.nlm.nih.gov/pubmed/27214551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80465
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