p66Shc regulates renal vascular tone in hypertension-induced nephropathy

Renal preglomerular arterioles regulate vascular tone to ensure a large pressure gradient over short distances, a function that is extremely important for maintaining renal microcirculation. Regulation of renal microvascular tone is impaired in salt-sensitive (SS) hypertension–induced nephropathy, b...

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Pubblicato in:J Clin Invest
Autori principali: Miller, Bradley, Palygin, Oleg, Rufanova, Victoriya A., Chong, Andrew, Lazar, Jozef, Jacob, Howard J., Mattson, David, Roman, Richard J., Williams, Jan M., Cowley, Allen W., Geurts, Aron M., Staruschenko, Alexander, Imig, John D., Sorokin, Andrey
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922697/
https://ncbi.nlm.nih.gov/pubmed/27270176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75079
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