Therapeutic Benefits of Young, But Not Old, Adipose-Derived Mesenchymal Stem Cells in a Chronic Mouse Model of Bleomycin-Induced Pulmonary Fibrosis

The observation that pulmonary inflammatory lesions and bleomycin (BLM)-induced pulmonary fibrosis spontaneously resolve in young mice, while remaining irreversible in aged mice, suggests that impairment of pulmonary regeneration and repair is associated with aging. Since mesenchymal stem cells (MSC...

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Detalhes bibliográficos
Publicado no:Transl Res
Main Authors: Tashiro, Jun, Elliot, Sharon J., Gerth, David J., Xia, Xiaomei, Pereira-Simon, Simone, Choi, Rhea, Catanuto, Paola, Shahzeidi, Shahriar, Toonkel, Rebecca L., Shah, Rahil H., El Salem, Fadi, Glassberg, Marilyn K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922649/
https://ncbi.nlm.nih.gov/pubmed/26432923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2015.09.004
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