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Three-Dimensional Domain Swapping Changes the Folding Mechanism of the Forkhead Domain of FoxP1

The forkhead family of transcription factors (Fox) controls gene transcription during key processes such as regulation of metabolism, embryogenesis, and immunity. Structurally, Fox proteins feature a conserved DNA-binding domain known as forkhead. Interestingly, solved forkhead structures of members...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Medina, Exequiel, Córdova, Cristóbal, Villalobos, Pablo, Reyes, Javiera, Komives, Elizabeth A., Ramírez-Sarmiento, César A., Babul, Jorge
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922571/
https://ncbi.nlm.nih.gov/pubmed/27276253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.043
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