Evolution of the Transmission-Blocking Vaccine Candidates Pvs28 and Pvs25 in Plasmodium vivax: Geographic Differentiation and Evidence of Positive Selection

Transmission-blocking (TB) vaccines are considered an important tool for malaria control and elimination. Among all the antigens characterized as TB vaccines against Plasmodium vivax, the ookinete surface proteins Pvs28 and Pvs25 are leading candidates. These proteins likely originated by a gene dup...

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Bibliografske podrobnosti
izdano v:PLoS Negl Trop Dis
Main Authors: Chaurio, Ricardo A., Pacheco, M. Andreína, Cornejo, Omar E., Durrego, Ester, Stanley, Craig E., Castillo, Andreína I., Herrera, Sócrates, Escalante, Ananias A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922550/
https://ncbi.nlm.nih.gov/pubmed/27347876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004786
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