Global genetic diversity of the Plasmodium vivax transmission-blocking vaccine candidate Pvs48/45

BACKGROUND: Plasmodium vivax 48/45 protein is expressed on the surface of gametocytes/gametes and plays a key role in gamete fusion during fertilization. This protein was recently expressed in Escherichia coli host as a recombinant product that was highly immunogenic in mice and monkeys and induced...

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Bibliografski detalji
Izdano u:Malar J
Glavni autori: Vallejo, Andres F., Martinez, Nora L., Tobon, Alejandra, Alger, Jackeline, Lacerda, Marcus V., Kajava, Andrey V., Arévalo-Herrera, Myriam, Herrera, Sócrates
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828788/
https://ncbi.nlm.nih.gov/pubmed/27067024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1263-0
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