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Calibrating genomic and allelic coverage bias in single-cell sequencing
Artifacts introduced in whole-genome amplification (WGA) make it difficult to derive accurate genomic information from single-cell genomes and require different analytical strategies from bulk genome analysis. Here, we describe statistical methods to quantitatively assess the amplification bias resu...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922254/ https://ncbi.nlm.nih.gov/pubmed/25879913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7822 |
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