The Pseudomonas aeruginosa efflux pump MexGHI-OpmD transports a natural phenazine that controls gene expression and biofilm development

Redox-cycling compounds, including endogenously produced phenazine antibiotics, induce expression of the efflux pump MexGHI-OpmD in the opportunistic pathogen Pseudomonas aeruginosa. Previous studies of P. aeruginosa virulence, physiology, and biofilm development have focused on the blue phenazine p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sakhtah, Hassan, Koyama, Leslie, Zhang, Yihan, Morales, Diana K., Fields, Blanche L., Price-Whelan, Alexa, Hogan, Deborah A., Shepard, Kenneth, Dietrich, Lars E. P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922186/
https://ncbi.nlm.nih.gov/pubmed/27274079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600424113
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