Musashi-2 (MSI2) supports TGF-β signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis

Non-small cell lung cancer (NSCLC) has a 5-y survival rate of ∼16%, with most deaths associated with uncontrolled metastasis. We screened for stem cell identity-related genes preferentially expressed in a panel of cell lines with high versus low metastatic potential, derived from NSCLC tumors of Kra...

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Publicado en:Proc Natl Acad Sci U S A
Main Authors: Kudinov, Alexander E., Deneka, Alexander, Nikonova, Anna S., Beck, Tim N., Ahn, Young-Ho, Liu, Xin, Martinez, Cathleen F., Schultz, Fred A., Reynolds, Samuel, Yang, Dong-Hua, Cai, Kathy Q., Yaghmour, Khaled M., Baker, Karmel A., Egleston, Brian L., Nicolas, Emmanuelle, Chikwem, Adaeze, Andrianov, Gregory, Singh, Shelly, Borghaei, Hossein, Serebriiskii, Ilya G., Gibbons, Don L., Kurie, Jonathan M., Golemis, Erica A., Boumber, Yanis
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922167/
https://ncbi.nlm.nih.gov/pubmed/27274057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1513616113
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