Transplantation of iPSC-derived TM cells rescues glaucoma phenotypes in vivo

Glaucoma is a common cause of vision loss or blindness and reduction of intraocular pressure (IOP) has been proven beneficial in a large fraction of glaucoma patients. The IOP is maintained by the trabecular meshwork (TM) and the elevation of IOP in open-angle glaucoma is associated with dysfunction...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Zhu, Wei, Gramlich, Oliver W., Laboissonniere, Lauren, Jain, Ankur, Sheffield, Val C., Trimarchi, Jeffrey M., Tucker, Budd A., Kuehn, Markus H.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2016
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922164/
https://ncbi.nlm.nih.gov/pubmed/27274060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604153113
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