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Closed state-coupled C-type inactivation in BK channels

Ion channels regulate ion flow by opening and closing their pore gates. K(+) channels commonly possess two pore gates, one at the intracellular end for fast channel activation/deactivation and the other at the selectivity filter for slow C-type inactivation/recovery. The large-conductance calcium-ac...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yan, Jiusheng, Li, Qin, Aldrich, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922147/
https://ncbi.nlm.nih.gov/pubmed/27298368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607584113
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