Hypoxia-inducible factor 3A gene expression and methylation in adipose tissue is related to adipose tissue dysfunction

Recently, a genome-wide analysis identified DNA methylation of the HIF3A (hypoxia-inducible factor 3A) as strongest correlate of BMI. Here we tested the hypothesis that HIF3A mRNA expression and CpG-sites methylation in adipose tissue (AT) and genetic variants in HIF3A are related to parameters of A...

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Publicado no:Sci Rep
Main Authors: Pfeiffer, Susanne, Krüger, Jacqueline, Maierhofer, Anna, Böttcher, Yvonne, Klöting, Nora, El Hajj, Nady, Schleinitz, Dorit, Schön, Michael R., Dietrich, Arne, Fasshauer, Mathias, Lohmann, Tobias, Dreßler, Miriam, Stumvoll, Michael, Haaf, Thomas, Blüher, Matthias, Kovacs, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921806/
https://ncbi.nlm.nih.gov/pubmed/27346320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27969
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