A new quantitation method of protodioscin by HPLC–ESI-MS/MS in rat plasma and its application to the pharmacokinetic study

A specific high performance liquid chromatography tandem mass spectrometry (HPLC–MS/MS method) was established for determining the concentration of protodioscin (PG) in rat plasma after intragastric administration of its standard form. Ginsenoside Rb(1) was selected as the internal standard (IS). Th...

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Gepubliceerd in:Steroids
Hoofdauteurs: Zhang, Xinxin, Guo, Zengjun, Li, Jing, Ito, Yoichiro, Sun, Wenji
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921743/
https://ncbi.nlm.nih.gov/pubmed/26703445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2015.12.009
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