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A new quantitation method of protodioscin by HPLC–ESI-MS/MS in rat plasma and its application to the pharmacokinetic study

A specific high performance liquid chromatography tandem mass spectrometry (HPLC–MS/MS method) was established for determining the concentration of protodioscin (PG) in rat plasma after intragastric administration of its standard form. Ginsenoside Rb(1) was selected as the internal standard (IS). Th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Steroids
Hauptverfasser: Zhang, Xinxin, Guo, Zengjun, Li, Jing, Ito, Yoichiro, Sun, Wenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921743/
https://ncbi.nlm.nih.gov/pubmed/26703445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2015.12.009
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