Leigh's disease: significance of the biochemical changes in brain.
Analysis of five brains from patients with Leigh's disease demonstrates an accumulation of thiamine pyrophosphate and a deficiency of thiamine triphosphate. The enzyme which converts thiamine pyrophosphate to thiamine triphosphate was normally active in two of these brains, suggesting that the inhib...
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| Publicado no: | J Neurol Neurosurg Psychiatry |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
1975
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC492163/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1206418/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jnnp.38.11.1100 |
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