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Leigh's disease: significance of the biochemical changes in brain.

Analysis of five brains from patients with Leigh's disease demonstrates an accumulation of thiamine pyrophosphate and a deficiency of thiamine triphosphate. The enzyme which converts thiamine pyrophosphate to thiamine triphosphate was normally active in two of these brains, suggesting that the...

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Dettagli Bibliografici
Autori principali: Murphy, J V, Craig, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1975
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC492163/
https://ncbi.nlm.nih.gov/pubmed/1206418
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