Leigh's disease: significance of the biochemical changes in brain.

Analysis of five brains from patients with Leigh's disease demonstrates an accumulation of thiamine pyrophosphate and a deficiency of thiamine triphosphate. The enzyme which converts thiamine pyrophosphate to thiamine triphosphate was normally active in two of these brains, suggesting that the inhib...

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Bibliografische Detailangaben

Veröffentlicht in:	J Neurol Neurosurg Psychiatry
Hauptverfasser:	Murphy, J V, Craig, L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMJ Publishing Group 1975
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC492163/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1206418/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jnnp.38.11.1100
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