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Leigh's disease: significance of the biochemical changes in brain.

Analysis of five brains from patients with Leigh's disease demonstrates an accumulation of thiamine pyrophosphate and a deficiency of thiamine triphosphate. The enzyme which converts thiamine pyrophosphate to thiamine triphosphate was normally active in two of these brains, suggesting that the inhib...

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Bibliografiske detaljer
Udgivet i:J Neurol Neurosurg Psychiatry
Principais autores: Murphy, J V, Craig, L
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 1975
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC492163/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1206418/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jnnp.38.11.1100
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