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Structural computational modeling of RNA aptamers

RNA aptamers represent an emerging class of biologics that can be easily adapted for personalized and precision medicine. Several therapeutic aptamers with desirable binding and functional properties have been developed and evaluated in preclinical studies over the past 25 years. However, for the ma...

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Publicat a:Methods
Autors principals: Xu, Xiaojun, Dickey, David D., Chen, Shi-Jie, Giangrande, Paloma H.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921272/
https://ncbi.nlm.nih.gov/pubmed/26972787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.03.004
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