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Identification of Dual-Tropic HIV-1 Using Evolved Neural Networks

Blocking the binding of the envelope HIV-1 protein to immune cells is a popular concept for development of anti-HIV therapeutics. R5 HIV-1 binds CCR5, X4 HIV-1 binds CXCR4, and dual-tropic HIV-1 can bind either coreceptor for cellular entry. R5 viruses are associated with early infection and over ti...

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Publicado en:Biosystems
Main Authors: Fogel, Gary B., Lamers, Susanna L., Liu, Enoch S., Salemi, Marco, McGrath, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921197/
https://ncbi.nlm.nih.gov/pubmed/26419858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biosystems.2015.09.007
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