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Depletion of Regulatory T Cells Induces High Numbers of Dendritic Cells and Unmasks a Subset of Anti-Tumour CD8(+)CD11c(+) PD-1(lo) Effector T Cells
Natural regulatory T (Treg) cells interfere with multiple functions, which are crucial for the development of strong anti-tumour responses. In a model of 4T1 mammary carcinoma, depletion of CD25(+)Tregs results in tumour regression in Balb/c mice, but the mechanisms underlying this process are not f...
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| Publicado en: | PLoS One |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4920347/ https://ncbi.nlm.nih.gov/pubmed/27341421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157822 |
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