Rapid Bioorthogonal Chemistry Turn-on through Enzymatic or Long Wavelength Photocatalytic Activation of Tetrazine Ligation

Rapid bioorthogonal reactivity can be induced by controllable, catalytic stimuli using air as the oxidant. Methylene blue (4 μM) irradiated with red light (660 nm) catalyzes the rapid oxidation of a dihydrotetrazine to a tetrazine thereby turning on reactivity toward trans-cyclooctene dienophiles. A...

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Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Zhang, Han, Trout, William S., Liu, Shuang, Andrade, Gabriel A., Hudson, Devin A., Scinto, Samuel L., Dicker, Kevin T., Li, Yi, Lazouski, Nikifar, Rosenthal, Joel, Thorpe, Colin, Jia, Xinqiao, Fox, Joseph M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920269/
https://ncbi.nlm.nih.gov/pubmed/27078610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b02168
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