Lamellipodia are crucial for haptotactic sensing and response

Haptotaxis is the process by which cells respond to gradients of substrate-bound cues, such as extracellular matrix proteins (ECM); however, the cellular mechanism of this response remains poorly understood and has mainly been studied by comparing cell behavior on uniform ECMs with different concent...

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Veröffentlicht in:J Cell Sci
Hauptverfasser: King, Samantha J., Asokan, Sreeja B., Haynes, Elizabeth M., Zimmerman, Seth P., Rotty, Jeremy D., Alb, James G., Tagliatela, Alicia, Blake, Devon R., Lebedeva, Irina P., Marston, Daniel, Johnson, Heath E., Parsons, Maddy, Sharpless, Norman E., Kuhlman, Brian, Haugh, Jason M., Bear, James E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920251/
https://ncbi.nlm.nih.gov/pubmed/27173494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.184507
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