Llwytho...

2- and 6-O-sulfated proteoglycans have distinct and complementary roles in cranial axon guidance and motor neuron migration

The correct migration and axon extension of neurons in the developing nervous system is essential for the appropriate wiring and function of neural networks. Here, we report that O-sulfotransferases, a class of enzymes that modify heparan sulfate proteoglycans (HSPGs), are essential to regulate neur...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Development
Prif Awduron: Tillo, Miguel, Charoy, Camille, Schwarz, Quenten, Maden, Charlotte H., Davidson, Kathryn, Fantin, Alessandro, Ruhrberg, Christiana
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920156/
https://ncbi.nlm.nih.gov/pubmed/27048738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.126854
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