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Microfluidic manufacture of rt-PA-loaded echogenic liposomes

Echogenic liposomes (ELIP), loaded with recombinant tissue-type plasminogen activator (rt-PA) and microbubbles that act as cavitation nuclei, are under development for ultrasound-mediated thrombolysis. Conventional manufacturing techniques produce a polydisperse rt-PA-loaded ELIP population with onl...

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Detalhes bibliográficos
Publicado no:Biomed Microdevices
Main Authors: Kandadai, Madhuvanthi A., Mukherjee, Prithviraj, Shekhar, Himanshu, Shaw, George J., Papautsky, Ian, Holland, Christy K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920071/
https://ncbi.nlm.nih.gov/pubmed/27206512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10544-016-0072-0
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