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Plasmin-loaded echogenic liposomes for ultrasound-mediated thrombolysis

Plasmin, a direct fibrinolytic, shows a significantly superior hemostatic safety profile compared to recombinant tissue plasminogen activator (rtPA), the only FDA approved thrombolytic for the treatment of acute ischemic stroke. The improved safety of plasmin is attributed to the rapid inhibition of...

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Detalhes bibliográficos
Publicado no:Transl Stroke Res
Main Authors: Kandadai, Madhuvanthi A., Meunier, Jason M., Hart, Kimberley, Holland, Christy K., Shaw, George J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298464/
https://ncbi.nlm.nih.gov/pubmed/25411015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-014-0376-4
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