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Partial Loss of the Glutamate Transporter GLT-1 Alters Brain Akt and Insulin Signaling in a Mouse Model of Alzheimer’s Disease
The glutamate transporter GLT-1 (also called EAAT2 in humans) plays a critical role in regulating extracellular glutamate levels in the central nervous system (CNS). In Alzheimer’s disease (AD),EAAT2 loss is associated with neuropathology and cognitive impairment. In keeping with this, we have repor...
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| Publicado no: | J Alzheimers Dis |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4920068/ https://ncbi.nlm.nih.gov/pubmed/25589729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-142304 |
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