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Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer’s Disease

Alzheimer’s disease is characterized by redistribution of the tau protein pool from soluble to aggregated states. Aggregation forms proteolytically stable core polymers restricted to the repeat domain, and this binding interaction has prion-like properties. We have compared the binding properties of...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Lai, Robert Y. K., Harrington, Charles R., Wischik, Claude M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919914/
https://ncbi.nlm.nih.gov/pubmed/27070645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom6020019
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