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The Involvement of Acetaldehyde in Ethanol-Induced Cell Cycle Impairment

Background: Hepatocytes metabolize the vast majority of ingested ethanol. This metabolic activity results in hepatic toxicity and impairs the ability of hepatocytes to replicate. Previous work by our group has shown that ethanol metabolism results in a G2/M cell cycle arrest. The intent of these stu...

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Bibliografiske detaljer
Udgivet i:Biomolecules
Main Authors: Scheer, Marc A., Schneider, Katrina J., Finnigan, Rochelle L., Maloney, Eamon P., Wells, Mark A., Clemens, Dahn L.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919912/
https://ncbi.nlm.nih.gov/pubmed/27043646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom6020017
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