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Optimal protein-folding codes from spin-glass theory.

Protein-folding codes embodied in sequence-dependent energy functions can be optimized using spin-glass theory. Optimal folding codes for associative-memory Hamiltonians based on aligned sequences are deduced. A screening method based on these codes correctly recognizes protein structures in the &qu...

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Detalhes bibliográficos
Main Authors: Goldstein, R A, Luthey-Schulten, Z A, Wolynes, P G
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC49199/
https://ncbi.nlm.nih.gov/pubmed/1594594
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