Associative memory Hamiltonians for structure prediction without homology: Alpha-helical proteins

Energy landscape theory is used to obtain optimized energy functions for predicting protein structure, without using homology information. At short sequence separation the energy functions are associative memory Hamiltonians constructed from a database of folding patterns in nonhomologous proteins a...

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Autores principales: Hardin, Corey, Eastwood, Michael P., Luthey-Schulten, Zaida, Wolynes, Peter G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2000
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC18901/
https://ncbi.nlm.nih.gov/pubmed/11114172
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