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Associative memory Hamiltonians for structure prediction without homology: Alpha-helical proteins

Energy landscape theory is used to obtain optimized energy functions for predicting protein structure, without using homology information. At short sequence separation the energy functions are associative memory Hamiltonians constructed from a database of folding patterns in nonhomologous proteins a...

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Detalhes bibliográficos
Main Authors: Hardin, Corey, Eastwood, Michael P., Luthey-Schulten, Zaida, Wolynes, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18901/
https://ncbi.nlm.nih.gov/pubmed/11114172
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