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Associative memory Hamiltonians for structure prediction without homology: Alpha-helical proteins

Energy landscape theory is used to obtain optimized energy functions for predicting protein structure, without using homology information. At short sequence separation the energy functions are associative memory Hamiltonians constructed from a database of folding patterns in nonhomologous proteins a...

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Bibliografiske detaljer
Main Authors: Hardin, Corey, Eastwood, Michael P., Luthey-Schulten, Zaida, Wolynes, Peter G.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18901/
https://ncbi.nlm.nih.gov/pubmed/11114172
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