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Myeloid-Specific Blockade of Notch Signaling Attenuates Choroidal Neovascularization through Compromised Macrophage Infiltration and Polarization in Mice

Macrophages have been recognized as an important inflammatory component in choroidal neovascularization (CNV). However, it is unclear how these cells are activated and polarized, how they affect angiogenesis and what the underlining mechanisms are during CNV. Notch signaling has been implicated in m...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Dou, Guo-Rui, Li, Na, Chang, Tian-Fang, Zhang, Ping, Gao, Xiang, Yan, Xian-Chun, Liang, Liang, Han, Hua, Wang, Yu-Sheng
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919651/
https://ncbi.nlm.nih.gov/pubmed/27339903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28617
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