The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance

Receptor-interacting protein kinase 3 (RIPK3) mediates necroptosis, a form of programmed cell death that promotes inflammation in various pathological conditions, suggesting that it might be a privileged pharmacological target. However, its function in glucose homeostasis and obesity has been unknow...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gautheron, Jérémie, Vucur, Mihael, Schneider, Anne T., Severi, Ilenia, Roderburg, Christoph, Roy, Sanchari, Bartneck, Matthias, Schrammen, Peter, Diaz, Mauricio Berriel, Ehling, Josef, Gremse, Felix, Heymann, Felix, Koppe, Christiane, Lammers, Twan, Kiessling, Fabian, Van Best, Niels, Pabst, Oliver, Courtois, Gilles, Linkermann, Andreas, Krautwald, Stefan, Neumann, Ulf P., Tacke, Frank, Trautwein, Christian, Green, Douglas R., Longerich, Thomas, Frey, Norbert, Luedde, Mark, Bluher, Matthias, Herzig, Stephan, Heikenwalder, Mathias, Luedde, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919522/
https://ncbi.nlm.nih.gov/pubmed/27323669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11869
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