The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance

Receptor-interacting protein kinase 3 (RIPK3) mediates necroptosis, a form of programmed cell death that promotes inflammation in various pathological conditions, suggesting that it might be a privileged pharmacological target. However, its function in glucose homeostasis and obesity has been unknow...

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Udgivet i:Nat Commun
Main Authors: Gautheron, Jérémie, Vucur, Mihael, Schneider, Anne T., Severi, Ilenia, Roderburg, Christoph, Roy, Sanchari, Bartneck, Matthias, Schrammen, Peter, Diaz, Mauricio Berriel, Ehling, Josef, Gremse, Felix, Heymann, Felix, Koppe, Christiane, Lammers, Twan, Kiessling, Fabian, Van Best, Niels, Pabst, Oliver, Courtois, Gilles, Linkermann, Andreas, Krautwald, Stefan, Neumann, Ulf P., Tacke, Frank, Trautwein, Christian, Green, Douglas R., Longerich, Thomas, Frey, Norbert, Luedde, Mark, Bluher, Matthias, Herzig, Stephan, Heikenwalder, Mathias, Luedde, Tom
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919522/
https://ncbi.nlm.nih.gov/pubmed/27323669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11869
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