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Decreased antimony uptake and overexpression of genes of thiol metabolism are associated with drug resistance in a canine isolate of Leishmania infantum

Visceral leishmaniasis (VL) caused by the protozoan parasite Leishmania infantum, is one of the most important zoonotic diseases affecting dogs and humans in the Mediterranean area. The presence of infected dogs as the main reservoir host of L. infantum is regarded as the most significant risk for p...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Parasitol Drugs Drug Resist
Hauptverfasser: Gómez Pérez, Verónica, García-Hernandez, Raquel, Corpas-López, Victoriano, Tomás, Ana M., Martín-Sanchez, Joaquina, Castanys, Santiago, Gamarro, Francisco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919363/
https://ncbi.nlm.nih.gov/pubmed/27317865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2016.04.003
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