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Decreased antimony uptake and overexpression of genes of thiol metabolism are associated with drug resistance in a canine isolate of Leishmania infantum

Visceral leishmaniasis (VL) caused by the protozoan parasite Leishmania infantum, is one of the most important zoonotic diseases affecting dogs and humans in the Mediterranean area. The presence of infected dogs as the main reservoir host of L. infantum is regarded as the most significant risk for p...

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Detalhes bibliográficos
Publicado no:Int J Parasitol Drugs Drug Resist
Main Authors: Gómez Pérez, Verónica, García-Hernandez, Raquel, Corpas-López, Victoriano, Tomás, Ana M., Martín-Sanchez, Joaquina, Castanys, Santiago, Gamarro, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919363/
https://ncbi.nlm.nih.gov/pubmed/27317865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2016.04.003
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