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Measurements of Deposition, Lung Surface Area and Lung Fluid for Simulation of Inhaled Compounds

Modern strategies in drug development employ in silico techniques in the design of compounds as well as estimations of pharmacokinetics, pharmacodynamics and toxicity parameters. The quality of the results depends on software algorithm, data library and input data. Compared to simulations of absorpt...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Fröhlich, Eleonore, Mercuri, Annalisa, Wu, Shengqian, Salar-Behzadi, Sharareh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919356/
https://ncbi.nlm.nih.gov/pubmed/27445817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00181
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