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Measurements of Deposition, Lung Surface Area and Lung Fluid for Simulation of Inhaled Compounds

Modern strategies in drug development employ in silico techniques in the design of compounds as well as estimations of pharmacokinetics, pharmacodynamics and toxicity parameters. The quality of the results depends on software algorithm, data library and input data. Compared to simulations of absorpt...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Fröhlich, Eleonore, Mercuri, Annalisa, Wu, Shengqian, Salar-Behzadi, Sharareh
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919356/
https://ncbi.nlm.nih.gov/pubmed/27445817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00181
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