cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase.
The antiinflammatory glucocorticoids are potent inhibitors of cyclooxygenase, a key regulator of prostaglandin synthesis; yet, the mechanism(s) by which this occurs is not fully understood. We have cloned a 4.1-kilobase (kb) cDNA, distinct from the previously cloned cyclooxygenase (2.8 kb), that con...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1992
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49193/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1594589/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.11.4888 |
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