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Loss of function mutation in glutamic pyruvate transaminase 2 (GPT2) causes developmental encephalopathy

Intellectual disability is genetically heterogeneous, and it is likely that many of the responsible genes have not yet been identified. We describe three siblings with isolated, severe developmental encephalopathy. After extensive uninformative genetic and metabolic testing, whole exome sequencing i...

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Publicado en:J Inherit Metab Dis
Autores principales: Celis, Katrina, Shuldiner, Scott, Haverfield, Eden V., Cappell, Joshua, Yang, Rongze, Gong, Da-Wei, Chung, Wendy K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919120/
https://ncbi.nlm.nih.gov/pubmed/25758935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10545-015-9824-x
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