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Role of the Long Non-Coding RNA MAPT-AS1 in Regulation of Microtubule Associated Protein Tau (MAPT) Expression in Parkinson's Disease

Studies investigating the pathogenic role of the microtubule associated protein tau (MAPT) gene in Parkinson’s disease (PD) have indicated that DNA methylation of the promoter region is aberrant in disease, leading to dysregulated MAPT expression. We examined two potential regulators of MAPT gene ex...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Coupland, Kirsten G., Kim, Woojin S., Halliday, Glenda M., Hallupp, Marianne, Dobson-Stone, Carol, Kwok, John B. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919105/
https://ncbi.nlm.nih.gov/pubmed/27336847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157924
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