DNA Methylation of MAPT Gene in Parkinson's Disease Cohorts and Modulation by Vitamin E In Vitro

BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder for which environmental factors influence disease risk and may act via an epigenetic mechanism. The microtubule-associated protein tau (MAPT) is a susceptibility gene for idiopathic PD. METHODS: Methylation levels were determi...

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Main Authors: Coupland, Kirsten G., Mellick, Goerge D., Silburn, Peter A., Mather, Karen, Armstrong, Nicola J., Sachdev, Perminder S., Brodaty, Henry, Huang, Yue, Halliday, Glenda M., Hallupp, Marianne, Kim, Woojin S., Dobson-Stone, Carol, Kwok, John B.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074263/
https://ncbi.nlm.nih.gov/pubmed/24375821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.25784
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