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Synthetic Modification of Manzamine A via Grubbs Metathesis. Novel Structures with Enhanced Antibacterial and Antiprotozoal Properties
A strategy for the structural modification of biologically important alkene-containing natural products via ring-opening olefin metathesis is described. Exposure of manzamine A 1 to the second-generation Grubbs catalyst in the presence of ethylene leads to the formation of 2 and 4. The antibacterial...
Guardat en:
| Publicat a: | Org Lett |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918910/ https://ncbi.nlm.nih.gov/pubmed/17918854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol701799c |
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