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Constitutive synthesis of tumor necrosis factor in the thymus.

Although tumor necrosis factor (TNF) is a major mediator of endotoxic shock, the normal function of TNF that has preserved this protein throughout mammalian evolution remains unknown. If the protein serves a role in normal development or homeostasis, it must be produced under physiologic conditions....

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Bibliographic Details
Main Authors: Giroir, B P, Brown, T, Beutler, B
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC49188/
https://ncbi.nlm.nih.gov/pubmed/1594585
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