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Pitt–Hopkins Syndrome and Differential Diagnosis: A Molecular and Clinical Challenge

Pitt–Hopkins syndrome is an emerging neurodevelopmental disorder caused by haploinsufficiency of the TCF4 gene on chromosome 18q21. It is characterized by severe intellectual disability, seizures, microcephaly, constipation and a distinctive facial gestalt. Although the overlapping phenotype of micr...

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Detalhes bibliográficos
Publicado no:J Pediatr Genet
Main Authors: Marangi, Giuseppe, Zollino, Marcella
Formato: Artigo
Idioma:Inglês
Publicado em: Georg Thieme Verlag KG 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918722/
https://ncbi.nlm.nih.gov/pubmed/27617128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0035-1564570
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