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Role of mechanical strain-activated PI3K/Akt signaling pathway in pelvic organ prolapse

Mechanical loading on pelvic supports contributes to pelvic organ prolapse (POP). However, the underlying mechanisms remain to be elucidated. Our previous study identified that mechanical strain induced oxidative stress (OS) and promoted apoptosis and senescence in pelvic support fibroblasts. The ai...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: LI, BING-SHU, GUO, WEN-JUN, HONG, LI, LIU, YAO-DAN, LIU, CHENG, HONG, SHA-SHA, WU, DE-BIN, MIN, JIE
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918563/
https://ncbi.nlm.nih.gov/pubmed/27176043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5264
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