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Collagen metabolic disorder induced by oxidative stress in human uterosacral ligament-derived fibroblasts: A possible pathophysiological mechanism in pelvic organ prolapse

Pelvic organ prolapse (POP) is a global health problem, for which the pathophysiological mechanism remains to be fully elucidated. The loss of extracellular matrix protein has been considered to be the most important molecular basis facilitating the development of POP. Oxidative stress (OS) is a wel...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: LIU, CHENG, YANG, QING, FANG, GUI, LI, BING-SHU, WU, DE-BIN, GUO, WEN-JUN, HONG, SHA-SHA, HONG, LI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805094/
https://ncbi.nlm.nih.gov/pubmed/26936098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.4919
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