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Synthesis and evaluation of new 2-aminothiophenes against Mycobacterium tuberculosis
Tuberculosis (TB) and its drug resistant forms kills more people than any other infectious disease. This fact emphasizes the need to identify new drugs to treat TB. 2-Aminothiophenes (2AT) have been reported to inhibit Pks13, a validated anti-TB drug target. We synthesized a library of 42 2AT compou...
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| Publicado no: | Org Biomol Chem |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918453/ https://ncbi.nlm.nih.gov/pubmed/27251120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob00821f |
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