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Quantifying and understanding the fitness effects of protein mutations: Laboratory versus nature

The last decade has seen a growing number of experiments aimed at systematically mapping the effects of mutations in different proteins, and of attempting to correlate their biophysical and biochemical effects with organismal fitness. While insightful, systematic laboratory measurements of fitness e...

詳細記述

保存先:
書誌詳細
出版年:Protein Sci
主要な著者: Boucher, Jeffrey I., Bolon, Daniel N. A., Tawfik, Dan S.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918414/
https://ncbi.nlm.nih.gov/pubmed/27010590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2928
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