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Combining HDAC inhibitors with oncolytic virotherapy for cancer therapy

Histone deacetylase (HDAC) enzymes play a critical role in the epigenetic regulation of cellular functions and signaling pathways in many cancers. HDAC inhibitors (HDACi) have been validated for single use or in combination with other drugs in oncologic therapeutics. An even more novel combination t...

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Detalhes bibliográficos
Publicado no:Oncolytic Virother
Main Authors: Nakashima, Hiroshi, Nguyen, Tran, Chiocca, Ennio Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918398/
https://ncbi.nlm.nih.gov/pubmed/27512681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S66081
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