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Critical analysis of an oncolytic herpesvirus encoding granulocyte-macrophage colony stimulating factor for the treatment of malignant melanoma

Oncolytic viruses that selectively lyse tumor cells with minimal damage to normal cells are a new area of therapeutic development in oncology. An attenuated herpesvirus encoding the granulocyte-macrophage colony stimulating factor (GM-CSF), known as talimogene laherparepvec (T-VEC), has been identif...

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Dettagli Bibliografici
Pubblicato in:Oncolytic Virother
Autori principali: Hughes, Tasha, Coffin, Robert S, Lilley, Caroline E, Ponce, Rafael, Kaufman, Howard L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918360/
https://ncbi.nlm.nih.gov/pubmed/27512660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S36701
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